| Code | Name | Synonym |
| ET-129 | Mal(3-Me)-AMCHC | 4-[(metylmaleimido)methyl]cyclohexane-1-carboxylic acid // (1r,4r)-4-[(3-methyl-2,5-dioxopyrrol-1- yl)methyl]cyclohexane-1-carboxylic acid |
| CAS | 71738-82-4 |  |
| Formula | C13H17NO4 | |
| MW | 251.3 | |
| Purity | >99% | |
| Storage | +2 ... +8 °C | |
| Note | Introduction of methyl group at maleimide core improves stability of maleimide-thiol conjugates. Access article |
|
| Code | Name | Synonym |
| ET-066 | Mal-AMCHC-OSu | SMCC // trans-N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate // N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate |
| CAS | 71875-81-5, 64987-85-5 |  |
| Formula | C16H18N2O6 | |
| MW | 334.3 | |
| Purity | >99% | |
| Storage | +2 ... +8 °C | |
| Note | Used as a linker for ADC construction. ACS Omega, 2019, 8834; DOI: 10.1021/acsomega.9b00430. | |
| Code | Name | Synonym |
| ET-174 | Mal-AMCHC-N-Propargylamide | MCC-Yne // trans‐4‐[(2,5‐dioxo‐2,5‐dihydro‐1H‐pyrrol‐1‐ yl)methyl]‐N‐(prop‐2‐yn‐1‐yl)cyclohexane‐1‐carboxamide // SMCC Propargyl amide // Maleimido-AMCHC-Propargylamide // Mal-AMCHC-N-Propynyl |
| CAS | 2027476-42-0, 1036847-90-1 (cis,trans) |  |
| Formula | C15H18N2O3 | |
| MW | 274.3 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | Used as a bio-conjugation reagent for antibody-drug-conjugate synthesis using Click-Chemistry. WO2019154120A1; US20160303253A1; US20170360770A1; Govindan, S. V. et. al. J. Med. Chem. 2008, 6916, DOI:10.1021/jm800719t. | |
| Code | Name | Synonym |
| AA-150 | H-Abu(3-N3).HCl (2S,3R) | (2S,3R)-2-amino-3-azidobutanoic acid hydrochloride |
| CAS |  |
|
| Formula | C4H9ClN4O2 | |
| MW | 180.6 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | H-Abu(3-N3) is incorporated into peptides and proteins that can be further selectively modified using Staudinger ligation or Click-chemistry. | |
| Code | Name | Synonym |
| AA-149 | H-Abu(3-N3).HCl (2S,3S) | (2S,3S)-2-amino-3-azidobutanoic acid hydrochloride |
| CAS |  |
|
| Formula | C4H9ClN4O2 | |
| MW | 180.6 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | H-Abu(3-N3) is incorporated into peptides and proteins that can be further selectively modified using Staudinger ligation or Click-chemistry. | |
| Code | Name | Synonym |
| FM-261 | Fmoc-Abu(3-NH2).HCl(2S,3S) | 2-(Fmoc-amino)-3-amino butanoic acid // Fmoc-allo-azaThr // Fmoc-L-allo-azaThr-OH |
| CAS | 244052-24-2, 788808-40-2 (net) |  |
| Formula | C19H21ClN2O4 | |
| MW | 376.8 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Code | Name | Synonym |
| FM-181 | Fmoc-Abu(3-N3) (2R,3R) | (2R,3R)-(Fmoc-amino)-3-azidobutanoic acid |
| CAS | 1229394-75-5 |  |
| Formula | C19H18N4O4 | |
| MW | 366.4 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | Protected building-block for the synthesis of 2,3-diaminobutanoic acid containing peptides and also for "click" reactions. Eur. J. Org. Chem. (2010), (13), 2536-2543. DOI:10.1002/ejoc.200901345. | |
| Code | Name | Synonym |
| FM-208 | Fmoc-Abu(3-N3) (2R,3S) | (2R,3S)-(Fmoc-amino)-3-azidobutanoic acid |
| CAS | 1932349-21-7 |  |
| Formula | C19H18N4O4 | |
| MW | 366.4 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Code | Name | Synonym |
| FM-197 | Fmoc-Abu(3-N3) (2S,3R) | (2S,3R)-(Fmoc-amino)-3-azidobutanoic acid |
| CAS | 146306-79-8 |  |
| Formula | C19H18N4O4 | |
| MW | 366.4 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | Protected building-block for the synthesis of 2,3-diaminobutanoic acid containing peptides and also for "click" reactions. ChemMedChem (2017), 12(15), 1169-1172. DOI:10.1002/cmdc.201700300. | |
| Code | Name | Synonym |
| FM-175 | Fmoc-Abu(3-N3) (2S,3S) | (2S,3S)-(Fmoc-amino)-3-azidobutanoic acid |
| CAS | 131669-42-6 |  |
| Formula | C19H18N4O4 | |
| MW | 366.4 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | Protected building-block for the synthesis of 2,3-diaminobutanoic acid containing peptides and also for "click" reactions. Journal of Natural Products (2017), 80(9), 2484-2491. DOI:10.1021/acs.jnatprod.7b00359; ChemMedChem (2017), 12(15), 1169-1172. DOI:10.1002/cmdc.201700300; Mendelsohn, Brian Alan PCT Int. Appl. (2015), WO 2015183978 A1. |
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