1...456...65

Code Name Synonym
FM-186 Fmoc-Abu(3-Alloc-amino) (2R,3R) 2-(Fmoc-amino)-3-(Alloc-amino)butanoic acid // Fmoc-D-allo-azaThr(Alloc) // Fmoc-D-allo-azaThr(Alloc)-OH
CAS 2382679-02-7 /upload/more_svg/small/small_fm-186.svg
Formula C23H24N2O6
MW 424.4
Purity >98%
Storage +2 ... +8 °C
Code Name Synonym
FM-259 Fmoc-Abu(3-Alloc-amino) (2R,3S) 2-(Fmoc-amino)-3-(Alloc-amino)butanoic acid (2R,3S) // Fmoc-D-azaThr(Alloc)-OH
CAS 1983436-80-1 rel /upload/small/small_fm-259.svg
Formula C23H24N2O6
MW 424.5
Purity >98%
Storage +2 ... +8 °C
Note Used as a building-block to introduce D-aza-Thr into peptides. For synthesis of Teixobactin analogues see Nowick, J.S. et al J.Org.Chem. 2020, 1331, DOI: 10.1021/acs.joc.9b02631.
Code Name Synonym
FM-196 Fmoc-Abu(3-Alloc-amino) (2S,3R) 2-(Fmoc-amino)-3-(Alloc-amino)butanoic acid (2S,3R) // Fmoc-azaThr(Alloc) // Fmoc-L-azaThr(Alloc)-OH
CAS 2381842-52-8 /upload/more_svg/small/small_FM-196.svg
Formula C23H24N2O6
MW 424.5
Purity >98%
Storage +2 ... +8 °C
Code Name Synonym
FM-184 Fmoc-Abu(3-Alloc-amino) (2S,3S) 2-(Fmoc-amino)-3-(Alloc-amino)butanoic acid // Fmoc-allo-azaThr(Alloc) // Fmoc-L-allo-azaThr(Alloc)-OH
CAS 1272754-91-2 /upload/more_svg/small/small_FM-184.svg
Formula C23H24N2O6
MW 424.4
Purity >98%
Storage +2 ... +8 °C
Note Used as an orthogonally protected building-block in solid-phase peptide synthesis.
Code Name Synonym
FM-188 Fmoc-Abu(3-Boc-Amino) (2R,3R) 2-(Fmoc-amino)-3-(Boc-amino)butanoic acid // Fmoc-D-allo-azaThr(Boc) // Fmoc-D-allo-azaThr(Boc)-OH
CAS 1932033-81-2 /upload/more_svg/small/small_FM-188.svg
Formula C24H28N2O6
MW 440.5
Purity >99%
Storage +2 ... +8 °C
Note Used as a protected building-block in solid-phase peptide synthesis.
Code Name Synonym
FM-190 Fmoc-Abu(3-Boc-Amino) (2S,3S) 2-(Fmoc-amino)-3-(Boc-amino)butanoic acid (2S,3S) // Fmoc-allo-azaThr(Boc) // Fmoc-L-allo-azaThr(Boc)-OH
CAS 131669-43-7 /upload/more_svg/small/small_FM-190.svg
Formula C24H28N2O6
MW 440.5
Purity >98%
Storage +2 ... +8 °C
Note Used as a protected building-block in solid-phase peptide synthesis. J. Am. Chem. Soc. (2014), 136(18), 6754-6762. DOI:10.1021/ja502744a.
Code Name Synonym
FM-242 Fmoc-Abu(3-guanidino(Boc)2)(2S,3S) (2S,3S)‐3‐{[(E)‐{[(tert‐butoxy)carbonyl]amino}({[(tert‐ butoxy)carbonyl]imino})methyl]amino}‐2‐({[(9H‐fluoren‐9‐yl)methoxy]carbonyl}amino)butanoic acid
CAS n/a /upload/small/small_fm-242.svg
Formula C30H38N4O8
MW 582.7
Purity >98%
Storage +2 ... +8 °C
Note This material is a sterically hindered Agp (2-amino-3-guanidino propionic acid) analogue that is used as a building-block in solid-phase peptide synthesis.
Code Name Synonym
ET-093 Biotinyl-Aca biotinamidocaproate // 6-[biotinamido]hexanoate // 6-biotinylamino-hexanoic acid // N-(+)-biotinyl-6-aminohexanoic acid // N-biotinylcaproic Acid
CAS 72040-64-3 /upload/more_svg/small/small_ET-093.svg
Formula C16H27N3O4S
MW 357.5
Purity >98%
Storage +2 ... +8 °C
Code Name Synonym
ET-094 Biotinyl-Aca-OSu Biotin-6-aminohexanoic acid-N-hydroxysuccinimide ester // Biotinamidocaproate-N-hydroxysuccinimide ester // N-Succinimidyl N-biotinyl-6-aminocaproate // Succinimidyl 6-[biotinamido]hexanoate
CAS 72040-63-2 /upload/more_svg/small/small_ET-094.svg
Formula C20H30N4O6S
MW 454.5
Purity >98%
Storage +2 ... +8 °C
Note Biot-Aca-OSu is a biotinylation reagent containing aminocaproic acid linker that reacts with amines. Nature Medicine (2008), 14(8), 869-874.
DOI:10.1038/nm.1711; Nature Nanotech. (2010), 5(9), 660-665. DOI:10.1038/nnano.2010.148; Bioconjugate Chem. (2018), 29(2), 245-249. DOI:10.1021/acs.bioconjchem.7b00826; Chem.-Eur. J. (2018), 24(44), 11292-11296. DOI:10.1002/chem.201802365.
Code Name Synonym
ET-173 Fmoc-Aca-DIM Fmoc-Ddax-OH // (9H‐fluoren‐9‐yl)methyl N‐[6‐(4,4‐dimethyl‐2,6‐ dioxocyclohexylidene)‐6‐hydroxyhexyl]carbamate
CAS 2379561-08-5 /upload/small/small_et-173.svg
Formula C29H33NO5
MW 475.6
Purity >98%
Storage -15 ... -25 °C
Note Used as a next-generation traceless "helping hand" solubilizing tag in SPPS. Several Lysine residues are attached to this linker using Fmoc-SPPS. The solubilising tag can be removed with 1M hydrazine or hydroxylamine solution. This linker is more stable than its predecessor Fmoc-Ddae-OH. Kay, M. S. et. al. Org. Biomol. Chem. 2019, 10237, DOI: 10.1039/c9ob02012h.

1...456...65