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Code Name Synonym
ET-150 N3-TEMPO 4-azido-TEMPO // 4-Azido-2,2,6,6-tetramethyl-1-piperidinyloxy // 2,2,6,6-Tetramethyl-4-azide-piperidin-1-oxyl // 4-Azido-2,2,6,6-tetramethylpiperidin-1-yloxy
CAS 63697-61-0 /upload/more_svg/small/small_ET-150.svg
Formula C9H17N4O
MW 197.3
Purity >98%
Storage -15 ... -25 °C
Note N3-TEMPO is used as a reagent to attach stable radical TEMPO to other molecules using Staudinger ligation or Click-chemistry. Angew. Chem. Int. Ed. (2015), 54(23), 6814-6818. DOI:10.1002/anie.201501706; J. Am. Chem. Soc. (2017), 139(12), 4258-4261. DOI:10.1021/jacs.7b02648; J. Am. Chem. Soc. (2018), 140(2), 766-774. DOI:10.1021/jacs.7b11628.
Code Name Synonym
DI-125 Fmoc-TEPA(Boc3)-Suc 3‐[(2‐{[(tert‐butoxy)carbonyl](2‐{[(tert‐butoxy)carbonyl](2‐{[(tert‐butoxy)carbonyl][2‐({[(9H‐fluoren‐9‐yl)methoxy]carbonyl}amino)ethyl]amino}ethyl)amino}ethyl)amino}ethyl)carbamoyl]propanoic acid
CAS 2304536-78-3 /upload/small/small_di-125.svg
Formula C42H61N5O11
MW 812
Purity >98%
Storage +2 ... +8 °C
Note This reagent is used as a protected polyamine linker or side-chain for various applications. Klein, P. M.; Kern, S.; Lee, D.-J.; Schmaus, J.; Hoehn, M.; Gorges, J.; Kazmaier, U.; Wagner, E. Biomaterials (2018), 178, 630-642, DOI:10.1016/j.biomaterials.2018.03.031.
Code Name Synonym
DI-124 TEPA(HBBBH) 4,7,10-tri-Boc-tetraethylene pentamine // tert‐butyl N,N‐bis({2‐[(2‐aminoethyl)[(tert‐butoxy)carbonyl]amino]ethyl})carbamate // 4,7,10-tris(Boc)tetraethylenepentamine // Tp(boc3)
CAS 556082-09-8 /upload/small/small_di-124.svg
Formula C23H47N5O6
MW 489.7
Purity >98%
Storage +2 ... +8 °C
Note TEPA HBBBH is used as a protected polyamine linker or side-chain for various applications. Reineke, T. M. et al, J. Am. Chem. Soc. (2006), 128(25), 8176-8184. DOI:10.1021/ja0585580; Reineke, T. M. et al, Proc. Natl. Acad. Sci. USA (2009), 106(40), 16913-16918, DOI:10.1073/pnas.0904860106; Wagner, E. et al, Org. Lett. (2011), 13(7), 1586-1589, DOI:10.1021/ol200381z; Reineke, T. M. et al, Biomacromolecules (2014), 15(5), 1612-1624, DOI:10.1021/bm401870z.
Code Name Synonym
DI-120 Fmoc-TETA(Boc2)-Suc-OH 3-({2-[(tert-butoxycarbonyl)({2-[(tert- butoxycarbonyl)(2-{[(9H-fluoren-9- ylmethoxy)carbonyl]amino}ethyl)amino]ethyl})amino]ethyl}carbamoyl)propanoic acid
CAS n/a /upload/more_svg/small/small_di-120.svg
Formula C35H48N4O9
MW 668.8
Purity >98%
Storage +2 ... +8 °C
Note

Code Name Synonym
DI-121 H-TETA(Boc2)-H N2,N3-diBoc-triethylene tetramine // 4,7-di-Boc-1,4,7,10-tetraazadecane // tert-butyl N-(2-aminoethyl)-N-{2-[(2- aminoethyl)(tert- butoxycarbonyl)amino]ethyl}carbamate
CAS 206531-21-7 /upload/more_svg/small/small_di-121.svg
Formula C16H34N4O4
MW 346.5
Purity >98%
Storage +2 ... +8 °C
Note H-TETA(Boc2)-H is used as a protected polyamine linker and to produce dendrimer-like structures. J. Am. Chem. Soc. (2006), 128(25), 8176-8184. DOI:10.1021/ja0585580; J. Med. Chem. (2013), 56(23), 9471-9481. DOI:10.1021/jm400794z; PCT Int. Appl. (2018), WO 2018097403 A1.
Code Name Synonym
DI-104 1-(Boc-amino)-4,7,10-trioxa-13-tridecaneazide tert-butyl N-(3-{2-[2-(3-azidopropoxy)ethoxy]ethoxy}propyl)carbamate // Boc-TOTA-N3
CAS 1162070-33-8 /upload/more_svg/small/small_DI-104.svg
Formula C15H30N4O5
MW 346.4
Purity >98%
Storage +2 ... +8 °C
Code Name Synonym
ET-166 N3-C10H20-COOH 11-Azidoundecanoic acid // 11-Azido-undecanoic acid
CAS 118162-45-1 /upload/small/small_et-166.svg
Formula C11H21N3O2
MW 227.3
Purity >98%
Storage +2 ... +8 °C
Note Used as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. A substrate of lipoic acid ligase for labeling. Ting, A. Y. et. al. Nature Biotech. 2007, 1483, DOI:10.1038/nbt1355; Leatherbarrow R. J.; Tate E. W. et. al. Org. Biomol. Chem. 2008, 2308, DOI:10.1039/b803258k; Wnuk S. F. et. al. Eur. J. Med. Chem. 2018, 314, DOI:DOI:10.1016/j.ejmech.2018.02.017.
Code Name Synonym
ET-163 N3-C10H20-COOSu 2,5‐dioxopyrrolidin‐1‐yl 11‐azidoundecanoate // 11-azido undecanoic acid NHS ester // 11-azido undecanoic acid N-hydroxysuccinimide ester
CAS 850080-13-6 /upload/small/small_et-163.svg
Formula C15H24N4O4
MW 324.4
Purity >98% (HPLC)
Storage +2 ... +8 °C
Note Used as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. Bundle, D. R. et al Organic & Biomolecular Chem. (2006), 4(1), 142-154. DOI:10.1039/B513595H; Liu, J.-N. et al Biomacromolecules (2009), 10(4), 877-883. DOI:10.1021/bm8014076; Zundel, M. A. et al PCT Int. Appl. (2005), WO 2005035553.
Code Name Synonym
ET-117 AMCA-OSu 7-amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester // N-succinimidyl 7-amino-4-methyl-3-coumarinylacetate // AMCA-NHS // succinimidyl-7-amino-4-methylcoumarin-3-acetate
CAS 113721-87-2 /upload/svg/small/small_et-117.svg
Formula C16H14N2O6
MW 330.3
Purity >95%
Storage +2 ... +8 °C

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