| Code | Name | Synonym |
| ET-084 | N3-AEEA.CHA | N3-AEEA.CHA // N3-AEEAc.CHA // 8-azido-3,6-dioxaoctanoic acid cyclohexylamine salt // cyclohexanaminium {2-[2-(2l5-triaz-1-en-2-yn-1-yl)ethoxy]ethoxy}acetate // [2-(2-azidoethoxy)ethoxy]acetic acid cyclohexylamine salt |
| CAS | 2098500-94-6, 882518-90-3 net |  |
| Formula | C |
|
| MW | 288.3 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | Used as a linker to produce drug conjugates via Click-chemistry and in other applications. Chen et al Bioconjugate Chem. (2009), 20(12), 2331-2341. DOI:10.1021/bc900339x; Rhee et al Biomacromolecules (2012), 13(8), 2333-2338. DOI:10.1021/bm300578p; Huang et al Org. Lett. (2018), 20(20), 6526-6529. DOI:10.1021/acs.orglett.8b02849; Ciulli et al Brit. UK Pat. Appl. (2018), GB 2554071 A 20180328. | |
| Code | Name | Synonym |
| ET-089 | N3-AEEA-OK | N3-AEEA K salt // N3-AEEAc.K // 8-azido-3,6-dioxaoctanoic acid potassium salt // potassium 2‐[2‐(2‐azidoethoxy)ethoxy]acetate // N3-Ado potassium salt |
| CAS | 882518-90-3 net |  |
| Formula | C6H10KN3O4 | |
| MW | 227.3 | |
| Purity | >99% | |
| Storage | +2 ... +8 °C | |
| Note | Used as a linker to produce drug conjugates via Click-chemistry and in other applications. Chen et al Bioconjugate Chem. (2009), 20(12), 2331-2341. DOI:10.1021/bc900339x; Rhee et al Biomacromolecules (2012), 13(8), 2333-2338. DOI:10.1021/bm300578p; Huang et al Org. Lett. (2018), 20(20), 6526-6529. DOI:10.1021/acs.orglett.8b02849; Ciulli et al Brit. UK Pat. Appl. (2018), GB 2554071 A 20180328. | |
| Code | Name | Synonym |
| ET-135 | N3-AEEA-OtBu | azido-AEEA tert-butyl ester // tert-butyl 2-[2-(2-azidoethoxy)ethoxy]acetate |
| CAS | 251564-45-1 |  |
| Formula | C10H19N3O4 | |
| MW | 245.3 | |
| Purity | >97% (HPLC) | |
| Storage | +2 ... +8 °C | |
| Code | Name | Synonym |
| ET-085 | N3-AEEA-AEEA | 17-azido-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid |
| CAS | 1254054-60-8 |  |
| Formula | C12H22N4O7 | |
| MW | 334.3 | |
| Purity | >97% | |
| Storage | -15 ... -25 °C | |
| Code | Name | Synonym |
| ET-137 | N3-AEEEA.CHA | 11-azido-3,6,9-trioxaundecanoic acid cyclohexylammonium salt // azido-PEG3-carboxylate // cyclohexylammonium 2-{2-[2-(2- azidoethoxy)ethoxy]ethoxy}acetate |
| CAS | 172531-37-2 net |  |
| Formula | C14H28N4O5 | |
| MW | 332.4 | |
| Purity | >98% (TLC) | |
| Storage | -15...-25 °C | |
| Code | Name | Synonym |
| CH-054 | trans-4-(Azidomethyl)cyclohexanecarboxylic acid | N3-AMCHC // N3-trans-MCHC-OH |
| CAS | 170811-10-6 |  |
| Formula | C8H13N3O2 | |
| MW | 183.2 | |
| Purity | >99% | |
| Storage | +2 ... +8 °C | |
| Note | N3-AMCHC is used as a protected Tranexamic acid building block that can be used in peptide synthesis. The azido-group can be selectively modified using Staudinger ligation or Click-chemistry or transformed into amino-group under neutral conditions. | |
| Code | Name | Synonym |
| ET-155 | (N3)2-DAPOA.DCHA | N‐cyclohexylcyclohexanaminium 2‐[(1,3‐ diazidopropan‐2‐yl)oxy]acetate |
| CAS | n/a |  |
| Formula | C17H31N7O3 | |
| MW | 381.48 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | (N3)2-DAPOA.DCHA can be used in peptide synthesis as a linker that can be further modified at the azido-groups using Staudinger ligation or Click-chemistry. This material can be used as a building block for dendrimeric structures. | |
| Code | Name | Synonym |
| ET-127 | Azido diglycine.DCHA | N-(2-azidoacetyl)-glycine DCHA salt // azido diglycine DCHA salt // azido glycylglycine DCHA salt // N3-diglycine.DCHA // 2-(2-azidoacetamido)acetic acid dicyclohexylamine salt |
| CAS | 855750-87-7 (net) |  |
| Formula | C16H29N5O3 | |
| MW | 339.4 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | N3-Gly-Gly is used as a linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. ACS Macro Letters (2014), 3(3), 291-294. DOI:10.1021/mz5000575. | |
| Code | Name | Synonym |
| ET-128 | Azido triglycine | N-(2-azidoacetyl)-glycylglycine // azido triglycine // azido glycylglycylglycine // N3-triglycine // 2-[2-(2-azidoacetamido)acetamido]acetic acid |
| CAS | 1993176-75-2 |  |
| Formula | C6H9N5O4 | |
| MW | 215.2 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C | |
| Note | N3-Gly-Gly-Gly is used as a linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. | |
| Code | Name | Synonym |
| ET-130 | Azido pentaglycine | azidoacetyl tetraglycine // N3-Gly-Gly-Gly-Gly-Gly-OH // N3-(Gly)5-OH // N3-GGGGG-OH // 2-(2-{2-[2-(2-azidoacetamido)acetamido]acetamido}acetamido)acetic acid |
| CAS | 2250433-77-1 |  |
| Formula | C10H15N7O6 | |
| MW | 329.3 | |
| Purity | >98% | |
| Storage | +2 ... +8 °C |
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