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Code Name Synonym
FM-250 Fmoc-Phe(4-NH-Poc) Fmoc-L-Aph(Poc)-OH // Fmoc-L-Phe(4-NH-Poc)-OH // Fmoc-4Aph(Poc) // Fmoc-L-4Aph(Poc)-OH // Fmoc-L-4-Aph(Poc)-OH // Fmoc-p-amino-Phe(Poc)-OH // Fmoc-L-Phe(4-NH-Poc)-OH // Fmoc-4Aph(Pryoc) // Fmoc-L-4Aph(Pryoc)-OH // Fmoc-L-4-Aph(Pryoc)-OH // Fmoc-p-amino-Phe(Pryoc)-OH
CAS n/a /upload/small/small_fm-250.svg
Formula C28H24N2O6
MW 484.5
Purity >98%
Storage +2 ... +8 °C
Note Used as an orthogonally protected building block in solid-phase peptide synthesis. Poc-group can be further modified using Click-chemistry.
Code Name Synonym
FM-219 Fmoc-Phe-ACC {7-[(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-phenylpropanamido]-2-oxochromen-4-yl}acetic acid
CAS 2250437-40-0 /upload/more_svg/small/small_fm-219.svg
Formula C35H28N2O7
MW 588.6
Purity >98%
Storage +2 ... +8 °C
Code Name Synonym
FM-220 Fmoc-Phe(4-N3) Fmoc-4-azidophenylalanine // Fmoc-4-azido-L-phenylalanine // Fmoc-p-azido-Phe-OH // Fmoc-Phe(N3)-OH // Fmoc-p-azidophenylalanine // Fmoc-phenylalanine-azide
CAS 163217-43-4 /upload/more_svg/small/small_fm-220.svg
Formula C24H20N4O4
MW 428.4
Purity >98%
Storage -15 ... -25 °C
Note Used in solid-phase peptide synthesis. The azido-funcionality can be further utilized to cross-link various functionalities to peptides or proteins utilizing Staudinger ligation or click-chemistry. Nano Letters (2015), 15(1), 603-609. DOI:10.1021/nl504079q; Angew. Chem. Int. Ed. (2013), 52(45), 11920-11924. DOI:10.1002/anie.201303467; J. Am. Chem. Soc. (2017), 139(17), 6152-6159. DOI:10.1021/jacs.7b01072.
Code Name Synonym
FM-165 Fmoc-ACC Fmoc-7-aminocoumarin-4-acetic acid // 7-N-(Fluorenylmethoxycarbonyl)aminocoumarin-4- acetic acid // Fmoc-ACA // Fmoc-ACAC
CAS 378247-75-7 /upload/more_svg/small/small_FM-165.svg
Formula C26H19NO6
MW 441.4
Purity >97%
Storage +2 ... +8 °C
Note Fmoc-ACA-OH is incorporated into peptides as Fluorogenic marker for protease substrates.JACS (2002), 124(50), 14868-14870. DOI:10.1021/ja027477q; JOC (2002), 67(3), 910-915. DOI:10.1021/jo016140o; DOI:10.1073/pnas.1318548111; J. Med. Chem. (2018), 61(12), 5222-5234. DOI:10.1021/acs.jmedchem.8b00026.
Code Name Synonym
DI-128 Fmoc-Cystamine.HCl (9H‐fluoren‐9‐yl)methyl N‐{2‐[(2‐ azaniumylethyl)disulfanyl]ethyl}carbamate chloride // mono-Fmoc-cystamine hydrochloride
CAS n/a /upload/small/small_di-128.svg
Formula C19H23ClN2O2S2
MW 411
Purity >98%
Storage +2 ... +8 °C
Note Fmoc-cystamine is used in SPPS as a linker for various applications. Bryan et al J. Am. Chem. Soc. (2004), 126(28), 8640-8641. DOI:10.1021/ja048433f; Cao et al J. Org. Chem. (2011), 76(18), 7423-7430. DOI:10.1021/jo201199k; Zhang et al Biomaterials (2018), 163, 14-24. DOI:10.1016/j.biomaterials.2018.02.023; Liu et al ACS Nano (2018), 12(8), 8129-8137. DOI:10.1021/acsnano.8b02980.
Code Name Synonym
DI-129 Fmoc-Cystamine-Suc 3‐[(2‐{[2‐({[(9H‐fluoren‐9‐ yl)methoxy]carbonyl}amino)ethyl]disulfanyl}ethyl)carbamoyl]propanoic acid // Succinoyl-Fmoc-Cystamine // 1-(9H-fluoren-9-yl)-3,12-dioxo-2-oxa-7,8-dithia-4,11-diazapentadecan-15-oic acid
CAS 946849-80-5 /upload/small/small_di-129.svg
Formula C23H26N2O5S2
MW 474.6
Purity >98%
Storage +2 ... +8 °C
Note Fmoc-cystamine-Suc is used in SPPS as a conjugation linker for various applications. Yang, Z. et. al. Chem. Comm., 2012, 395, DOI:10.1039/C1CC16250K; Liu, B.; Yang, Z.; Ding, D. et. al. Analytical Chem., 2016, 3872, DOI:10.1021/acs.analchem.6b00023; Yang, Z. et. al. Angew. Chem. Int. Ed. 2018, 1813, DOI:10.1002/anie.201710237; Qian, H. et. al. Bioorg. Chem. 2019, 102945, DOI:10.1016/j.bioorg.2019.102945.
Code Name Synonym
DI-119 Fmoc-DETA(Boc)-Suc-OH 3-({2-[(tert-butoxycarbonyl)(2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}ethyl)amino]ethyl}carbamoyl)propanoic acid
CAS 1373763-34-8 /upload/more_svg/small/small_DI-119.svg
Formula C28H35N3O7
MW 525.6
Purity >98%
Storage +2 ... +8 °C
Code Name Synonym
DI-096 Spermine(FBBSuc) N1-Fmoc-N4,N9-di-Boc-N12-succinoyl-spermine // 3-({3-[(tert-butoxycarbonyl)({4-[(tert-butoxycarbonyl)(3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propyl)amino]butyl})amino]propyl}carbamoyl)propanoic acid
CAS 1263046-90-7 /upload/more_svg/small/small_di-096.svg
Formula C39H56N4O9
MW 724.9
Purity >97%
Storage +2 ... +8 °C
Note Spermine FBBSuc is used as a linker in various applications.
Code Name Synonym
DI-049 Fmoc-EDA.HCl mono-Fmoc ethylene diamine hydrochloride // N-Fmoc-ethylenediamine hydrochloride
CAS 391624-46-7 , 166410-32-8 net /upload/more_svg/small/small_DI-049.svg
Formula C17H19ClN2O2
MW 318.8
Purity >99%
Storage -15 ... -25 °C
Code Name Synonym
DI-110 Fmoc-EDA-N3 9H-fluoren-9-ylmethyl N-(2-azidoethyl)carbamate
CAS 432507-62-5 /upload/more_svg/small/small_di-110.svg
Formula C17H16N4O2
MW 308.3
Purity >99%
Storage +2 ... +8 °C

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