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Code Name Synonym
AA-148 H-Phe(4-N3) 4-Azido-L-phenylalanine // 3-(p-Azidophenyl)-L-alanine // 4-Azidophenylalanine // p-Azido-L-phenylalanine // p-Azidophenylalanine // H-4-Azido-Phe // Phe(pN3) // para-azido-Phe // pAzF // AzPhe
CAS 33173-53-4 /upload/small/small_aa-148.svg
Formula C9H10N4O2
MW 206.2
Purity >98%
Storage -15 ... -25 °C
Note H-Phe(4-N3) is used in protein biosynthesis as unnatural amino acid for genetic code expansion. The azido-funcionality can be further utilized to cross-link various functionalities to proteins utilizing click-chemistry. DOI:10.1126/science.1084772; DOI:10.1038/nature08817; DOI:10.1038/nature14095;
The azido-functionality is IR-active and can be used in protein active site electrostatic environment studies. DOI:10.1038/nchembio.167;
The azide-handle can also be used for protein PEGylation or attachment to antibodies using click-chemistry. DOI:10.1021/acssynbio.7b00316; U.S. (2018).

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