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Code Name Synonym
FM-260 Fmoc-Glu(Biot-TOTA) Fmoc-Glu(biotinyl-PEG)-OH // Fmoc-L-Gln(biotinyl-PEG)-OH // Fmoc-L-Glu(biotinyl-PEG)-OH // N-alpha-Fmoc-N-gamma-(N-biotinyl-3-(2-(2-(3-aminopropyloxy)-ethoxy)-ethoxy)-propyl)-L-glutamine
CAS 817169-73-6 /upload/small/small_fm-260.svg
Formula C40H55N5O10S
MW 798
Purity >98%
Enantiopurity >99.9%
Storage +2 ... +8 °C
Note Biotin-containing amino acid with good solubility in DMF for use in SPPS. Frey A. et. al. Bioconj. Chem., 2018, 4020, DOI:10.1021/acs.bioconjchem.8b00583; Robinson J. A. et. al. Science 2010, 1010, DOI:10.1126/science.1182749.
Code Name Synonym
CH-014 Fmoc-1,2-cis-ACHC (1R,2S+1S,2R) Fmoc-cis-2-aminocyclohexane carboxylic acid
CAS 194471-85-7 /upload/more_svg/small/small_CH-014.svg
Formula C22H23NO4
MW 365.4
Purity >99%
Storage +2 ... +8 °C
Specification Link
Code Name Synonym
CH-016 Fmoc-1,2-trans-ACHC (1R,2R+1S,2S) Fmoc-trans-2-aminocyclohexane carboxylic acid (1R,2R+1S,2S)
CAS 381241-08-3 /upload/more_svg/small/small_CH-016.svg
Formula C22H23NO4
MW 365.4
Purity >99%
Storage +2 ... +8 °C
Specification Link
Code Name Synonym
CH-020 Fmoc-1,3-cis-ACHC (1S,3R+1R,3S) Fmoc-cis-3-aminocyclohexane carboxylic acid
CAS 312965-05-2 /upload/more_svg/small/small_CH-020.svg
Formula C22H23NO4
MW 365.4
Purity >99%
Storage +2 ... +8 °C
Specification Link
Code Name Synonym
CH-021 Fmoc-1,4-cis-ACHA Fmoc-cis-4-aminocyclohexane acetic acid
CAS 1217675-84-7 /upload/more_svg/small/small_CH-021.svg
Formula C23H25NO4
MW 379.4
Purity >99%
Storage +2 ... +8 °C
Specification Link
Code Name Synonym
CH-022 Fmoc-1,4-cis-ACHC Fmoc-cis-4-aminocyclohexane carboxylic acid
CAS 147900-45-6 /upload/more_svg/small/small_CH-022.svg
Formula C22H23NO4
MW 365.4
Purity >99%
Storage +2 ... +8 °C
Specification Link
Code Name Synonym
CH-023 Fmoc-1,4-trans-ACHA Fmoc-trans-4-aminocyclohexane acetic acid
CAS 1217650-00-4 /upload/more_svg/small/small_CH-023.svg
Formula C23H25NO4
MW 379.4
Purity >99%
Storage +2 ... +8 °C
Specification Link
Code Name Synonym
CH-024 Fmoc-1,4-trans-ACHC Fmoc-trans-4-aminocyclohexane carboxylic acid
CAS 147900-46-7 /upload/more_svg/small/small_CH-024.svg
Formula C22H23NO4
MW 365.4
Purity >99%
Storage +2 ... +8 °C
Specification Link
Code Name Synonym
CH-038 Fmoc-AMCHC Fmoc-Tranexamic acid // trans-4-(Fmoc-aminomethyl)cyclohexane carboxylic acid // N-Fmoc-Tranexamic acid // Fmoc-trans-4-Amc-OH
CAS 167690-53-1 /upload/small/small_ch-038.svg
Formula C23H25NO4
MW 379.5
Purity >99%
Storage +2 ... +8 °C
Note Fmoc-AMCHC is used as a linker in solid-phase peptide synthesis to construct various biologically active conjugates. This fragment is present in many Antibody Drug Conjugates (Kadcyla®, IMMU-132). J. Med. Chem. (2016), 59(5), 1761-1775.  DOI:10.1021/acs.jmedchem.5b01210; Behrens et al PCT Int. Appl. (2011), WO 2011089255 A1; Zhu et al PCT Int. Appl. (2019), WO 2019011166 A1.
Code Name Synonym
CH-056 Fmoc,Me-AMCHC Fmoc-N-methyl-tranexamic acid // trans-4-(Fmoc-methylaminomethyl)cyclohexane carboxylic acid
CAS 173690-50-1 /upload/more_svg/small/small/small_CH-056.svg
Formula C24H27NO4
MW 393.5
Purity >99%
Storage +2 ... +8 °C
Note Fmoc,Me-AMCHC is used as a protected N-methyl-Tranexamic acid building block that can be used in peptide synthesis. Tetrahedron Lett. (1996), 37(2), 263-6. DOI:10.1016/0040-4039(95)02145-0.

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