Code |
Name |
Synonym |
FM-260 |
Fmoc-Glu(Biot-TOTA) |
Fmoc-Glu(biotinyl-PEG)-OH // Fmoc-L-Gln(biotinyl-PEG)-OH // Fmoc-L-Glu(biotinyl-PEG)-OH // N-alpha-Fmoc-N-gamma-(N-biotinyl-3-(2-(2-(3-aminopropyloxy)-ethoxy)-ethoxy)-propyl)-L-glutamine |
CAS |
817169-73-6 |
 |
Formula |
C40H55N5O10S |
MW |
798 |
Purity |
>98% |
Enantiopurity |
>99.9% |
Storage |
+2 ... +8 °C |
Note |
Biotin-containing amino acid with good solubility in DMF for use in SPPS. Frey A. et. al. Bioconj. Chem., 2018, 4020, DOI:10.1021/acs.bioconjchem.8b00583; Robinson J. A. et. al. Science 2010, 1010, DOI:10.1126/science.1182749.
|
Code |
Name |
Synonym |
CH-014 |
Fmoc-1,2-cis-ACHC (1R,2S+1S,2R) |
Fmoc-cis-2-aminocyclohexane carboxylic acid |
CAS |
194471-85-7 |
 |
Formula |
C22H23NO4 |
MW |
365.4 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Specification |
Link |
Code |
Name |
Synonym |
CH-016 |
Fmoc-1,2-trans-ACHC (1R,2R+1S,2S) |
Fmoc-trans-2-aminocyclohexane carboxylic acid (1R,2R+1S,2S) |
CAS |
381241-08-3 |
 |
Formula |
C22H23NO4 |
MW |
365.4 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Specification |
Link |
Code |
Name |
Synonym |
CH-020 |
Fmoc-1,3-cis-ACHC (1S,3R+1R,3S) |
Fmoc-cis-3-aminocyclohexane carboxylic acid |
CAS |
312965-05-2 |
 |
Formula |
C22H23NO4 |
MW |
365.4 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Specification |
Link |
Code |
Name |
Synonym |
CH-021 |
Fmoc-1,4-cis-ACHA |
Fmoc-cis-4-aminocyclohexane acetic acid |
CAS |
1217675-84-7 |
 |
Formula |
C23H25NO4 |
MW |
379.4 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Specification |
Link |
Code |
Name |
Synonym |
CH-022 |
Fmoc-1,4-cis-ACHC |
Fmoc-cis-4-aminocyclohexane carboxylic acid |
CAS |
147900-45-6 |
 |
Formula |
C22H23NO4 |
MW |
365.4 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Specification |
Link |
Code |
Name |
Synonym |
CH-023 |
Fmoc-1,4-trans-ACHA |
Fmoc-trans-4-aminocyclohexane acetic acid |
CAS |
1217650-00-4 |
 |
Formula |
C23H25NO4 |
MW |
379.4 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Specification |
Link |
Code |
Name |
Synonym |
CH-024 |
Fmoc-1,4-trans-ACHC |
Fmoc-trans-4-aminocyclohexane carboxylic acid |
CAS |
147900-46-7 |
 |
Formula |
C22H23NO4 |
MW |
365.4 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Specification |
Link |
Code |
Name |
Synonym |
CH-038 |
Fmoc-AMCHC |
Fmoc-Tranexamic acid // trans-4-(Fmoc-aminomethyl)cyclohexane carboxylic acid // N-Fmoc-Tranexamic acid // Fmoc-trans-4-Amc-OH |
CAS |
167690-53-1 |
 |
Formula |
C23H25NO4 |
MW |
379.5 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Note |
Fmoc-AMCHC is used as a linker in solid-phase peptide synthesis to construct various biologically active conjugates. This fragment is present in many Antibody Drug Conjugates (Kadcyla®, IMMU-132). J. Med. Chem. (2016), 59(5), 1761-1775. DOI:10.1021/acs.jmedchem.5b01210; Behrens et al PCT Int. Appl. (2011), WO 2011089255 A1; Zhu et al PCT Int. Appl. (2019), WO 2019011166 A1. |
Code |
Name |
Synonym |
CH-056 |
Fmoc,Me-AMCHC |
Fmoc-N-methyl-tranexamic acid // trans-4-(Fmoc-methylaminomethyl)cyclohexane carboxylic acid |
CAS |
173690-50-1 |
 |
Formula |
C24H27NO4 |
MW |
393.5 |
Purity |
>99% |
Storage |
+2 ... +8 °C |
Note |
Fmoc,Me-AMCHC is used as a protected N-methyl-Tranexamic acid building block that can be used in peptide synthesis. Tetrahedron Lett. (1996), 37(2), 263-6. DOI:10.1016/0040-4039(95)02145-0. |