Fmoc-Pro(4-N3) (2S,4S)

Synonyms
Fmoc-(2S, 4S)-4-azidoproline // (2S,4S)-Fmoc-gamma-azidoproline // Fmoc-Azp (2S,4S) // Fmoc-4-azidoproline

ID

FM-177

Formula

C20H18N4O4

CAS

263847-08-1

MW

378.4

Purity

>98%

Storage

+2 ... +8 °C

Product image

References

Fmoc-Pro(4-N3) is incorporated into peptides and proteins that can be further selectively modified using Staudinger ligation or Click-chemistry. The Azido-group can be reduced to amino-group under neutral conditions. Angew. Chem. Int. Ed. (2010), 49(36), 6324-6327, S6324/1-S6324/23. DOI:10.1002/anie.201001851;
J. Am. Chem. Soc. (2013), 135(14), 5250-5253. DOI:10.1021/ja312143h; J. Med. Chem. (2018), 61(11), 5020-5033. DOI:10.1021/acs.jmedchem.8b00477.

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