H-Phe(4-N3).HCl

Synonyms
4-Azido-L-phenylalanine hydrochloride // 3-(p-Azidophenyl)-L-alanine Hydrochloride // 4-Azidophenylalanine Hydrochloride // p-Azido-L-phenylalanine Hydrochloride // p-Azidophenylalanine Hydrochloride // H-4-Azido-Phe.HCl // Phe(pN3).HCl // para-azido-Phe.HCl // N3Phe

ID

AA-147

Formula

C9H11ClN4O2

CAS

34670-43-4, 33173-53-4 net

MW

242.7

Purity

>98%

Isomeric purity

>99.9%

Storage

-15 to -25 °C

Product image

References

H-Phe(4-N3) is used in protein biosynthesis as unnatural amino acid for genetic code expansion. The azido-funcionality can be further utilized to cross-link various functionalities to proteins utilizing click-chemistry.

https://doi.org/10.1126/science.1084772

https://doi.org/10.1038/nature08817

https://doi.org/10.1038/nature14095

https://doi.org/10.1021/acscentsci.1c00499

The azido-functionality is IR-active and can be used in protein active site electrostatic environment studies.

https://doi.org/10.1038/nchembio.167

Angew. Chem. Int. Ed. 2022, 61, e202200648;

https://doi.org/10.1002/anie.202200648

The azide-handle can also be used for protein PEGylation or attachment to antibodies using click-chemistry.

https://doi.org/10.1021/acssynbio.7b00316

Methods, 2023, 219, 95-101

https://doi.org/10.1016/j.ymeth.2023.10.001

 

SIZE

PRICE

100G

EUR 3120

25G

EUR 2040

5G

EUR 510

1G

EUR 145

500MG

EUR 94

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