H-Phe(4-N3).HCl

Synonyms
4-Azido-L-phenylalanine hydrochloride // 3-(p-Azidophenyl)-L-alanine Hydrochloride // 4-Azidophenylalanine Hydrochloride // p-Azido-L-phenylalanine Hydrochloride // p-Azidophenylalanine Hydrochloride // H-4-Azido-Phe.HCl // Phe(pN3).HCl // para-azido-Phe.HCl

ID

AA-147

Formula

C9H11ClN4O2

CAS

34670-43-4 , 33173-53-4 net

MW

242.7

Purity

>98%

Storage

-15 ... -25°C

Product image

References

H-Phe(4-N3) is used in protein biosynthesis as unnatural amino acid for genetic code expansion. The azido-funcionality can be further utilized to cross-link various functionalities to proteins utilizing click-chemistry. DOI:10.1126/science.1084772; DOI:10.1038/nature08817; DOI:10.1038/nature14095;
The azido-functionality is IR-active and can be used in protein active site electrostatic environment studies. DOI:10.1038/nchembio.167;
The azide-handle can also be used for protein PEGylation or attachment to antibodies using click-chemistry. DOI:10.1021/acssynbio.7b00316; U.S. (2

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