Mal(Br2)-AMCHC

Synonyms
3,4-dibromo-maleimido-AMCHC // 3,4-dibromo-maleimido tranexamic acid // trans‐4‐[(3,4‐dibromo‐2,5‐dioxo‐2,5‐dihydro‐1H‐pyrrol‐1‐yl)methyl]cyclohexane‐1‐carboxylic acid

ID

ET-156

Formula

C12H13Br2NO4

CAS

2807037-12-1

MW

395

Purity

>99%

Storage

+2 to +8 °C

Product image

References

Mal(Br2)-AMCHC is used as a bio-conjugation reagent for antibody-drug-conjugate synthesis. The di-bromo maleimide is a novel conjugation tool that addresses the retro-Michael instability of simple thiosuccinimide linkage.

Chudasama V. et al. Drug Discovery Today: Tech. (2018), 30, 27-34. DOI:10.1016/j.ddtec.2018.07.002

Bioconjugate Chem. (2011), 22(2), 132-136; DOI:10.1021/bc1004685

J. Am. Chem. Soc. (2012), 134(3), 1847-1852; DOI:10.1021/ja210335f

Bioconjugate Chem. (2018), 29(2), 486-492; DOI:10.1021/acs.bioconjchem.7b00795.

SIZE

PRICE

5G

EUR 1000

1G

EUR 280

500MG

EUR 180

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