Biotinyl-TOTA

Synonyms
N-(13-amino-4,7,10-trioxatridecanyl)-D-biotinamide // Biotin-TOTA // 5‐[(3aS,4S,6aR)‐2‐oxo‐hexahydro‐1H‐thieno[3,4‐ d]imidazol‐4‐yl]‐N‐(3‐{2‐[2‐(3‐ aminopropoxy)ethoxy]ethoxy}propyl)pentanamide

ID

ET-161

Formula

C20H38N4O5S

CAS

183896-00-6

MW

446.6

Purity

>98%

Storage

+2 ... +8 °C

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References

This reagent is a water-soluble biotinylation reagent that can be coupled to carboxylic acids and various electrophiles. Hang et al J. Am. Chem. Soc. (2009), 131(13), 4967-4975. DOI:10.1021/ja810122f; Tinberg, C. E.; Khare, S. D.; Dou, J.; Doyle, L.; Nelson, J. W.; Schena, A.; Jankowski, W.; Kalodimos, C. G.; Johnsson, K.; Stoddard, B. L.; et al Nature  (2013), 501(7466), 212-216. DOI:10.1038/nature12443; Shajahan, A.; Parashar, S.; Goswami, S.; Ahmed, S. M.; Nagarajan, P.; Sampathkumar, S.-G. J. Am. Chem. Soc. (2017), 139(2), 693-700. DOI:10.1021/jacs.6b08894.

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