Fmoc-Phe(4-CH2-N3)

Synonyms
Fmoc-L-Phe(4-CH2-N3)-OH // Fmoc-p-azidomethyl-L-phenylalanine // Fmoc-para-methylazido-L-phenylalanine // Fmoc-para-azidomethyl-L-phenylalanine // Fmoc-pN3CH2Phe // Fmoc-pAMF // Fmoc-4-(Azidomethyl)-L-phenylalanine

ID

FM-252

Formula

C25H22N4O4

CAS

2375587-79-2

MW

442.5

Purity

>98%

Storage

+2 ... +8 °C

Product image

References

This material is used in antibody drug conjugates as a superior SPAAC reaction partner in comparison to H-Phe(4-N3). Bioconjugate Chem. (2014), 25(2), 351-361. DOI:10.1021/bc400490z. It can serve as a vibrational reporter of local protein environments after genetic incorporation into proteins.  J. Phys. Chem. B (2013), 117(30), 8987-8993. DOI:10.1021/jp4052598; Molina, Arturo PCT Int. Appl. (2019), WO 2019023316 A1.

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