pGlu-Pro-Arg-pNA.HCl

References

Hepsin chromogenic substrate, chromogenic substrate for Factor XI in plasma.

This substrate can be used for protein C determination.

This substrate has been used for the determination of kinetic constants of tryptase (EC 3.4.21.59) from guinea pig (Km = 0.24 – 0.26 mM) and human (Km = 0.24 – 0.43 mM). Pyr-Pro-Arg-pNA has also been used as substrate for the coagulation factor XIa. Km and kcat values for this substrate were 0.56 mM and 350 s⁻¹, respectively.