Fmoc-Dab(N3)

Synonyms
Fmoc-AHA // L-2-(Fmoc-amino)-4-azidobutanoic acid // (2S)-4-azido-2-(Fmoc-amino)butanoic acid // Fmoc-azidohomoalanine // Fmoc-L-gamma-azidohomoalanine Fmoc-Dab(N3)-OH // Fmoc-γ-azidohomoalanine

ID

FM-133

Formula

C19H18N4O4

CAS

942518-20-9

MW

366.4

Purity

>99%

Isomeric purity

>99.9%

Storage

+2 to +8 °C

Product image

References

Fmoc-Dab(N3) is incorporated into peptides that can be further selectively modified using Staudinger ligation or Click-chemistry. The azido-group can be reduced to give 2,4-diaminobutyric acid.

Nature 2007, 446, 1105–1109;

https://doi.org/10.1038/nature05757

Angew. Chem. Int. Ed. 2011, 50(22), 5207-5211;

https://doi.org/10.1002/anie.201008142

 

J. Am. Chem. Soc. 2017, 139(6), 2136-2139;

https://doi.org/10.1021/jacs.6b10809

 

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