ID |
FM-213 |
Formula |
C23H20N2O4 |
CAS |
1788861-35-7 |
MW |
388.4 |
Purity |
>98% |
Storage |
+2 to +8 °C |
References
Fmoc-MeDbz is used as a linker in peptide synthesis. It can be cyclysed into a N-acyl-N-methylacylurea using Nitrophenyl chloroformate.
J. Am. Chem.Soc. 2015, 137(22), 7197-7209. DOI:10.1021/jacs.5b03504;
J. Am. Chem.Soc. 2016, 138(15), 5069-5075. DOI:10.1021/jacs.5b13580;
J. Am. Chem.Soc. 2016, 138(41), 13461-13464. DOI:10.1021/jacs.6b05389;
Tetrahedron. Lett. 2018, 59(18), 1779-1782. DOI:10.1016/j.tetlet.2018.03.084;
Angew. Chem. Int. Ed. 2018, 57(8), 2105-2109. DOI:10.1002/anie.201711546.
Brik, A. et. al. Angew. Chem. Int. Ed. 2021, 60(13), 7333-7343. DOI:10.1002/anie.202016208.
Modified capping: DOI:10.1016/j.tetlet.2018.08.061.