Fmoc-MeDbz

Synonyms
3-(Fmoc-amino)-4-(methylamino)benzoic acid // 3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-(methylamino)benzoic acid

ID

FM-213

Formula

C23H20N2O4

CAS

1788861-35-7

MW

388.4

Purity

>98%

Storage

+2 to +8 °C

Product image

References

Fmoc-MeDbz is used as a linker in peptide synthesis. It can be cyclysed into a N-acyl-N-methylacylurea using Nitrophenyl chloroformate.

J. Am. Chem.Soc. 2015, 137(22), 7197-7209. DOI:10.1021/jacs.5b03504;

J. Am. Chem.Soc. 2016, 138(15), 5069-5075. DOI:10.1021/jacs.5b13580;

J. Am. Chem.Soc. 2016, 138(41), 13461-13464. DOI:10.1021/jacs.6b05389;

Tetrahedron. Lett. 2018, 59(18), 1779-1782. DOI:10.1016/j.tetlet.2018.03.084;

Angew. Chem. Int. Ed. 2018, 57(8), 2105-2109. DOI:10.1002/anie.201711546.

Brik, A. et. al. Angew. Chem. Int. Ed. 2021, 60(13), 7333-7343. DOI:10.1002/anie.202016208.

Modified capping: DOI:10.1016/j.tetlet.2018.08.061.

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