ID |
ET-157 |
Formula |
C18H15F5N2O6 |
CAS |
1887132-90-2 |
MW |
450.3 |
Purity |
>98% |
Isomeric purity |
>99.7% |
Storage |
+2 to +8 °C |
References
Mal-Dap(Boc)-OPfp is used in drug conjugate construction leading to more stable conjugates due to Dap neighbouring-group assistance. This strategy is widely used by Seagen and others. Lyon et al PCT Int. Appl. (2015), WO 2015057699 A2; Cong et al PCT Int. Appl. (2017), WO 2017196598 A1; Burke et al PCT Int. Appl. (2017), WO 2017096311 A1.
WO2021207701
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