Fmoc-AMCHC

Synonyms
Fmoc-Tranexamic acid // trans-4-(Fmoc-aminomethyl)cyclohexane carboxylic acid // N-Fmoc-Tranexamic acid

ID

CH-038

Formula

C23H25NO4

CAS

167690-53-1

MW

379.5

Purity

>99%

Storage

+2 ... +8 °C

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References

Fmoc-AMCHC is used as a linker in solid-phase peptide synthesis to construct various biologically active conjugates. This fragment is present in many Antibody Drug Conjugates (Kadcyla®, IMMU-132). J. Med. Chem. (2016), 59(5), 1761-1775.  DOI:10.1021/acs.jmedchem.5b01210; Behrens et al PCT Int. Appl. (2011), WO 2011089255 A1; Zhu et al PCT Int. Appl. (2019), WO 2019011166 A1.

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