ID |
ET-162 |
Formula |
C10H11Br2NO6 |
CAS |
n/a |
MW |
401 |
Purity |
>98% |
Storage |
+2 ... +8 °C |
References
Mal(Br2)-AEEA is used as a hydrophylic bio-conjugation reagent for antibody-drug-conjugate synthesis. The di-bromo maleimide is a novel conjugation tool that addresses the retro-Michael instability of simple thiosuccinimide linkage. Baker et al Organic & Biomolecular Chemistry (2014), 12(37), 7261-7269. DOI:10.1039/C4OB01550A; Jackson et al Molecular Pharmaceutics (2015), 12(11), 3986-3998. DOI:10.1021/acs.molpharmaceut.5b00432; Baker et al Organic & Biomolecular Chemistry (2017), 15(14), 2947-2952. DOI:10.1039/C7OB00220C.
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