Fmoc-Aca-DIM

Synonyms
Fmoc-Ddax-OH // (9H‐fluoren‐9‐yl)methyl N‐[6‐(4,4‐dimethyl‐2,6‐ dioxocyclohexylidene)‐6‐hydroxyhexyl]carbamate

ID

ET-173

Formula

C29H33NO5

CAS

2379561-08-5

MW

475.6

Purity

>98%

Storage

-15 ... -25 °C

Product image

References

Used as a next-generation traceless "helping hand" solubilizing tag in SPPS. Several Lysine residues are attached to this linker using Fmoc-SPPS. The solubilising tag can be removed with 1M hydrazine or hydroxylamine solution. This linker is more stable than its predecessor Fmoc-Ddae-OH. Kay, M. S. et. al. ChemRxiv 2019, 1-12.

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