ID |
ET-173 |
Formula |
C29H33NO5 |
CAS |
2379561-08-5 |
MW |
475.6 |
Purity |
>98%, white solid |
Storage |
-15 to -25 °C |
References
Used as a next-generation traceless "helping hand" solubilizing tag in SPPS. Several Lysine residues are attached to this linker using Fmoc-SPPS. The solubilising tag can be removed with 1M hydrazine or hydroxylamine solution. This linker is more stable than its predecessor Fmoc-Ddae-OH. Kay, M. S. et. al. Org. Biomol. Chem., 2019,17, 10237-10244.
https://doi.org/10.1039/C9OB02012H
Bioconjugate Chem. 2021, 32, 10, 2233–2244.
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