Fmoc-Ddax-Ala-OH

Synonyms
(2S)‐2‐{[1‐(4,4‐dimethyl‐2,6‐dioxocyclohexylidene)‐6‐({[(9H‐fluoren‐9‐yl)methoxy]carbonyl}amino)hexyl]amino}propanoic acid

ID

ET-179

Formula

C32H38N2O6

CAS

n/a

MW

546.7

Purity

>98%

Storage

+2 to +8 °C

Product image

References

Used as an Alanine-containing next-generation traceless "helping hand" solubilizing tag in SPPS. This solves the low reactivity issue of the tag with a peptide. Several Lysine residues are attached to this linker using Fmoc-SPPS. The solubilising tag can be removed with 1M hydrazine or hydroxylamine solution.

Kay, M. S. et. al. Org. Biomol. Chem. 2019, 10237, DOI: 10.1039/c9ob02012h.

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