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Mal-Dap(Boc)

Synonyms
N-alpha-Maleimido-N-beta-Boc-L-2,3-diaminopropionic acid // Mal-Dpr(Boc) // (S)-maleoyl-DPR(boc)-OH // mDPR(Boc) // Mal-L-PA-NH-Boc

ID	ET-180
Formula	C₁₂H₁₆N₂O₆
CAS	1491152-23-8
MW	284.3
Purity	>98%
Storage	+2 to +8 °C

References

Mal-Dap(Boc) is used in drug conjugate construction leading to more stable conjugates due to Dap neighbouring-group assistance. This strategy is widely used by Seattle Genetics and others.

PCT Int. Appl. (2015), WO 2015057699 A2;

PCT Int. Appl. (2017), WO 2017196598 A1.

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