Z-Phe-Arg-AMC.HCl

References

Z-Phe-Arg-AMC is a fluorogenic substrate for various serine proteases like cathepsins, kallikrein and plasmin. Substrate of papain, cruzain and trypsin. Absorption/emission of substrate = 330/390 nm (weak fluorescence) Absorption/emission of end product (AMC) = 342/441 nm (strong fluorescence). Levy M. A. et. al. J. Biol. Chem. 1996, 12517, DOI:10.1074/jbc.271.21.12517; Niles A. L. et. al. Anal. Biochem. 2007, 197, DOI:10.1016/j.ab.2007.04.007; Huck W. T. S. et. al. Angew. Chem. Int. Ed. 2018, 14065, DOI:10.1002/anie.201806944.