Fmoc-Ser(Psi(Me,Me)pro)-OH

References

Pseudoproline monomer for SPPS. This building-block can be successfully coupled with many amino-acids using modern coupling techniques avoiding the need for pseudoproline dipeptides and giving the possibility to introduce pseudoprolines in peptides containing non-natural or rare amino-acids. For use in SPPS please see:

J. Org. Chem., 2024, 89, 24, 18039–18046

https://doi.org/10.1021/acs.joc.4c01589

ACS Omega 2022, 7, 32, 28487–28492;

https://doi.org/10.1021/acsomega.2c03261

For coupling efficiency studies please refer to:

Senko, D. A. et. al. Amino Acids, 2021, 665;

https://doi.org/10.1007/s00726-021-02973-1