Fmoc-Thr(Psi(Me,Me)pro)-OH

Synonyms
Fmoc-L-Thr(Psi(Me,Me)pro)-OH // Fmoc-Thr(ΨMe,Mepro)-OH // (4S,5R)‐3‐{[(9H‐fluoren‐9‐yl)methoxy]carbonyl}‐2,2,5‐trimethyl‐1,3‐oxazolidine‐4‐carboxylic acid

ID

FM-268

Formula

C22H23NO5

CAS

2023823-19-8

MW

381.4

Purity

>99%

Storage

+2 to +8 °C

Product image

References

Threonine-derived Pseudoproline monomer for SPPS. This building-block can be successfully coupled with many amino-acids using modern coupling techniques avoiding the need for pseudoproline dipeptides and giving the possibility to introduce pseudoprolines in peptides containing non-natural or rare amino-acids. For coupling efficiency studies please refer to:

Senko, D. A. et. al. Amino Acids, 2021, 665;

https://doi.org/10.1007/s00726-021-02973-1

ACS Omega 2022, 7, 32, 28487–28492;

https://doi.org/10.1021/acsomega.2c03261

For use in SPPS please refer to:

https://doi.org/10.1016/j.tetlet.2022.154301

SIZE

PRICE

25G

EUR 425

5G

EUR 106

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