Fmoc-D-Sec(Xan)

Synonyms
Fmoc-D-Sec(Xan)-OH // Fmoc-D-Sec(Xanthyl)-OH // Fmoc-D-Selenocysteine(Xanthyl)-OH

ID

FM-273

Formula

C31H25NO5Se

CAS

n/a

MW

570.5

Purity

>98%

Storage

+2 to +8 °C

Product image

References

L-isomer content <0.1%

A bench-stable building-block with TFA-labile side-chain protecting group for introduction of D-Sec (D-Selenocysteine) into peptides by SPPS.

Liberation and deprotection of the peptides from the resin can be carried out using a standard 96:2:2 v/v TFA/TIS/H2O cocktail for 1.5h.

J. Pept. Sci. 2015, 53-59.

https://doi.org/10.1002/psc.2723

Alternatively for cleaner cleavage of Xanthyl-PG this mixture can be used: TFA/phenol/water/thioanisole/ethanedithiol.

Org. Biomol. Chem., 2019,17, 8533-8536.

https://doi.org/10.1039/C9OB01910C

Send an
enquiry

Product enquiry

Bapeks Ltd.

Rupnicu 4, Nordic Industrial Park

Olaine, LV-2114

Latvia / EU

VAT Reg.# LV40003006842


@2021 Bapeks Ltd. All rights reserved.