H-Lys(4-N3-Z).HCl

Synonyms
H-L-Lys(4-N3-Z)-OH // H-Lys(Z(4-N3))-OH // pAzZLys // H-Lys(Z-4-N3)-OH // (2S)-6-(4-Azido-benzyloxycarbonylamino)-2-amino-hexanoic acid hydrochloride // Nε-p-azidobenzyloxycarbonyl lysine // PABK

ID

AA-174

Formula

C14H20ClN5O4

CAS

2084913-49-3, 1513855-74-7 net

MW

357.8

Purity

>98%

Isomeric purity

>99.9%

Storage

+2 to +8 °C

Product image

References

Modified Lysine containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition.

Chem. Sci., 2016, 7, 7055-7060;

https://doi.org/10.1039/C6SC02615J

The Lysine can be decaged/deprotected using Staudinger reduction:

ChemBioChem, 2020, 21, 1-2, 141-148;

https://doi.org/10.1002/cbic.201900464

WO2013100132A1

WO2017030156A1

WO2021072167A1

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